Unveiling Druggable Pockets by Site-Specific Protein Modification: Beyond Antibody-Drug Conjugates
Frontiers in Chemistry
https://doi.org/10.3389/fchem.2020.586942
Published 21st October 2020
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design
Marija Sorokina, João M. C. Teixeira, Susana Barrera-Vilarmau, Reinhard Paschke, Ioannis Papasotiriou, João P. G. L. M. Rodrigues & Panagiotis L. Kastritis
Scientific Data volume 7, Article number: 309 (2020)
https://doi.org/10.1038/s41597-020-00652-6
Published 16th September 2020
Alternatively spliced isoforms of AUF1 regulate a miRNA-mRNA interaction differentially through their YGG motif
Lennart Sänger, Julian Bender, Katja Rostowski, Ralph Golbik, Carla Schmidt, Hauke Lilie, Sven-Erik Behrens & Susann Friedrich
RNA Biology 2020
https://doi.org/10.1080/15476286.2020.1822637
Published 14 September 2020
IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer
Unstructured regions of large enzymatic complexes control the availability of metabolites with signaling functions
Ioannis Skalidis, Christian Tüting & Panagiotis L. Kastritis
Cell Communication and Signaling volume 18, Article number: 136 (2020)
https://doi.org/10.1186/s12964-020-00631-9
Published 26th August 2020
Structural analysis of 70S ribosomes by cross-linking/mass spectrometry reveals conformational plasticity
Enhanced optical imaging properties of lipid nanocapsules as vehicles for fluorescent conjugated polymers
Paola Modicano, Paul Robert Neumann, Moritz Schüller, Joost Holthof, Fotis L.Kyrilis, Farzad Hamdi, Panagiotis L. Kastritis, Karsten Mäder, Lea Ann Dailey
European Journal of Pharmaceutics and Biopharmaceutics Volume 154, September 2020, Pages 297-308
https://doi.org/10.1016/j.ejpb.2020.07.017
Published 22nd July 2020
Constructing artificial respiratory chain in polymer compartments: Insights into the interplay between bo3 oxidase and the membrane
Cross-linking/mass spectrometry at the crossroads
Flexibility of intrinsically disordered degrons in AUX/IAA proteins reinforces auxin co-receptor assemblies
Michael Niemeyer, Elena Moreno Castillo, Christian H. Ihling, Claudio Iacobucci, Verona Wilde, Antje Hellmuth, Wolfgang Hoehenwarter, Sophia L. Samodelov, Matias D. Zurbriggen, Panagiotis L. Kastritis, Andrea Sinz & Luz Irina A. Calderón Villalobos
Nature Communications volume 11, Article number: 2277 (2020)
Published 08 May 2020