Macromolecular Crowding Induces a Binding Competent Transient Structure in Intrinsically Disordered Gab1

Tobias Gruber, Marc Lewitzky, Lisa Machner, Ulrich Weininger, Stephan M.Feller, Jochen Balbach

Journal of Molecular Biology, Volume 434, Issue 5, 15 March 2022, 167407


Available online 17 December 2021

Disorder-to-order transition of Synaptobrevin-2: Tracing the conformational diversity of a synaptic SNARE protein

Julia Hesselbarth, Carla Schmidt

Journal of Structural Biology Volume 214, Issue 1, March 2022, 107824


Available online 10 December 2021

Cross-Linking Mass Spectrometry for Investigating Protein Conformations and Protein–Protein Interactions─A Method for All Seasons

Lolita Piersimoni, Panagiotis L. Kastritis, Christian Arlt and Andrea Sinz

Chem. Rev. 2021, XXXX, XXX, XXX-XXX


Published 19th November 2021

Small but Mighty—The Emerging Role of snoRNAs in Hematological Malignancies

Jaime Calvo Sánchez and Marcel Köhn
Published 26th October 2021

Cross-Linking/Mass Spectrometry Combined with Ion Mobility on a timsTOF Pro Instrument for Structural Proteomics

Christian H. Ihling, Lolita Piersimoni, Marc Kipping and Andrea Sinz

Analytical Chemistry. 2021, 93, 33, 11442–11450
Published 10th August 2021

Effects of non-ionic and zwitterionic detergents on soluble proteins during native mass spectrometry experiments

Til Kundlacz, Julian Bender, Carla Schmidt

International Journal of Massspectrometry Volume 468, October 2021, 116652


Published 11th of June 2021

First 3D-Structural Data of Full-length Guanylyl Cyclase 1 in Rod-Outer-Segment Preparations   of Bovine Retina by Cross-linking/Mass Spectrometry

Anne Rehkamp, Dirk Tänzler, Christian Tüting, Panagiotis L. Kastritis, Claudio Iacobucci, Christian H. Ihling, Marc Kipping1, Karl-Wilhelm Koch, Andrea Sinz

Journal of Molecular Biology Volume 433, Issue 10, 14 May 2021, 166947


Published 14th May 2021

Oncogenic Potential of the Dual-Function Protein MEX3A

Marcell Lederer , Simon Müller, Markus Glaß , Nadine Bley, Christian Ihling, Andrea Sinz and Stefan Hüttelmaier 

Biology 2021 10(5), 415


Published 07th of May 2021

Detecting Protein Communities in Native Cell Extracts by Machine Learning: A Structural Biologist’s Perspective

Fotis L KyrilisJaydeep BelapurePanagiotis L Kastritis

Frontiers in Molecular Biosciences

Published 15th April 2021

An anti-HER2 nanobody binds to its antigen HER2 via two independent paratopes

Daniele Ubbiali, Marco Orlando, MaticKovačič, Claudio Iacobucci, Marta S. Semrau, Gregor Bajc, Sara Fortuna, Gregor Ilc, Barbara Medagli, Sandra Oloketuyi, Paola Storici, Andrea Sinz, Rita Grandori, Ariode Marco

International Journal of Biological Macromolecules


Published 14 April 2021

Integrative structure of a 10-megadalton eukaryotic pyruvate dehydrogenase complex from native cell extracts

Published 09th February 2021


Exploring Phosphoinositide Binding Using Native Mass Spectrometry

Julian Bender & Carla Schmidt

Phosphoinositides pp 157-175



Identification and initial characterization of POLIII-driven transcripts by msRNA-sequencing

Peter Zorn , Danny Misiak, Michael Gekle & Marcel Köhn

RNA Biology


Published 18th of January