The academic carrier of Manuel Weber started at his second year during the bachelor program at the University of Applied Science Mannheim. He accepted an exchange research internship at the Memorial University in Newfoundland, where he assisted in the study of the functional and structural charateristics of lung surfactant protein B.
During his bachelor and master studies he developed methods for the machine-learning aided Assessment/ Monitoring of Fermentation processes via Gas-Phase Ion-Mobility-Spectrometry and Mass Spectrometry at the Insitute for Instumental Analytics at the CHARISMA Competence Center Mannheim.
In the RTG2467 his PhD project is focusing on the analysis of the Parathyroid Hormone (PTH). The intrinsically disordered regions are suspected to mediate the formation and release of the functional PTH storage amyloid granules and are suspected to increase the signal response of the parathyroid hormone/ parathyroid hormone-related peptide G-protein-coupled-receptor. Manuel Weber will investigate these topics with in vitro Fibrillation-Assays, FRET experiments for receptor activation, in cell NMR, and cross-linking analysed by Mass Spectrometry.
Department of Physics
Biophysics Research Group, Prof. Jochen Balbach
06120 Halle (Saale)
Phone: +49 (0)345 – 5528554
Jochen Balbach (P2)