Milton T. Stubbs

Milton T. Stubbs

studied for a BSc in Physics at the University of Durham, UK, from 1988 to 1983, before obtaining a DPhil in Molecular Biophysics from the University of Oxford, UK, in 1986. From 1987-1991, he was a postdoctoral fellow at the Max Planck Institute for Biochemistry in Martinsried, Germany. He then moved to the Center of Structural Biochemistry at Karolinska Institute, Stockholm, Sweden, where he became an Assistant Professor in 1992. He then had a joint appointment as a senior research fellow at AKZO Organon, Netherlands and the Max Planck Institute for Biochemistry in Martinsried. In 1995, he started to work as a senior research fellow at the Department of Clinical Chemistry of the Ludwig Maximilians University in Munich, Germany. In 1996 he became the head of X-ray crystallography at the Institute of Pharmaceutical Chemistry, University of Marburg, Germany, before accepting a professorship in Physical Biotechnology at the MLU in 2002. He is director of research center ZIK HALOmem at the MLU.

Project within the RTG – Together with Stephan M. Feller

Key publications

Piechotta A, Parthier C, Kleinschmidt M, Gnoth K, Pillot T, Lues I, Demuth HU, Schilling S, Rahfeld JU, Stubbs MT. Structural and functional analyses of pyroglutamate-amyloid-β-specific antibodies as a basis for Alzheimer immunotherapy. J Biol Chem. 2017, 292: 12713-12724.

Parthier C, Stelter M, Ursel C, Fändrich U, Lilie H, Breithaupt C, Stubbs MT.  Structure of the Toll-Spätzle complex, a molecular hub in Drosophila development and innate immunity. Proc Natl Acad Sci USA. 2014, 111: 6281-6286.Simon C, Klose T, Herbst S, Han BG, Sinz A, Glaeser RM, Stubbs MT, Lilie H. Disulfide linkage and structure of highly stable yeast-derived virus-like particles of murine polyomavirus. J Biol Chem. 2014, 289: 10411-10418.