2024

Induction of oxidative- and endoplasmic-reticulum-stress dependent apoptosis in pancreatic cancer cell lines by DDOST knockdown

Richard Böhme, Andreas W. Schmidt, Nico Hesselbarth, Guido Posern, Andrea Sinz, Christian Ihling, Patrick Michl, Helmut Laumen, Jonas Rosendahl

Scientific Reports

Published September 2nd 2024

https://doi.org/10.1038/s41598-024-68510-8

APOBEC3C-mediated NF-κB activation enhances clear cell renal cell carcinoma progression

Nora Hase, Danny Misiak, Helge Taubert, Stefan Hüttelmaier, Michael Gekle, Marcel Köhn

Molecular Oncology

Published August 26th 2024

https://doi.org/10.1002/1878-0261.13721

Evaluating Imide-Based Mass Spectrometry-Cleavable Cross-Linkers for Structural Proteomics Studies

Alessio Di Ianni, Christian H. Ihling, Tomáš Vranka, Václav Matoušek, Andrea Sinz and Claudio Iacobucci

JACS Au

Published July 16th 2024

https://doi.org/10.1021/jacsau.4c00282

A Workflow for Improved Analysis of Cross-Linking Mass Spectrometry Data Integrating Parallel Accumulation-Serial Fragmentation with MeroX and Skyline

Juan Camilo Rojas Echeverri, Frank Hause, Claudio Iacobucci, Christian H Ihling, Dirk Tänzler, Nicholas Shulman, Michael Riffle, Brendan X MacLean, Andrea Sinz

Analytical Chemistry

Published May 14th 2024

https://doi.org/10.1021/acs.analchem.4c00829

Delineating organizational principles of the endogenous L-A virus by cryo-EM and computational analysis of native cell extracts

Lisa Schmidt, Christian Tüting, Fotis L. Kyrilis, Farzad Hamdi, Dmitry A. Semchonok, Gerd Hause, Annette Meister, Christian Ihling, Milton T. Stubbs, Andrea Sinz, Panagiotis L. Kastritis

Communications Biology

Published May 10th 2024

https://doi.org/10.1038/s42003-024-06204-7

Effect of Molecular Dynamics and Internal Water Contact on the Photophysical Properties of Red pH-Sensitive Proteins

Schmitt FJ, Mehmood AS, Tüting C, Phan HT, Reisdorf J, Rieder F, Ghane Golmohamadi F, Verma R, Kastritis PL, Laufer J

Biomacromolecules

Published January 2nd 2024

https://doi.org/10.1021/acs.biochem.3c00444

Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex

Fabian Giehler, Michael S. Ostertag, Thomas Sommermann, Daniel Weidl, Kai R. Sterz, Helmut Kutz, Andreas Moosmann, Stephan M. Feller, Arie Geerlof, Brigitte Biesinger, Grzegorz M. Popowicz, Johannes Kirchmair & Arnd Kieser

Nature Communications

Published January 10th 2024

https://doi.org/10.1038/s41467-023-44455-w

Rbfox1 controls alternative splicing of focal adhesion genes in cardiac muscle cells

Peter Zorn, Jaime Calvo Sánchez, Tala Alakhras, Barbara Schreier, Michael Gekle, Stefan Hüttelmaier, Marcel Köhn

Journal of Molecular Cell Biology
 
Published January 22nd 2024
 

RAVER1 hinders lethal EMT and modulates miR/RISC activity by the control of alternative splicing

Alice Wedler, Nadine Bley, Markus Glaß, Simon Müller, Laura Schian, Kingsley Benjamin Obika, Marcell Lederer, Claudia Misiak, Tommy Fuchs, Marcel Köhn, Roland Jacob, Tony Gutschner, Christian Ihling, Andrea Sinz, Stefan Hüttelmaier
 
Nucleic Acids Research
 
Published January 12th 2024