Structural basis of neurofibromin tetramerization and dimer-tetramer equilibrium
Shutian Si, Christian Tüting, Swanhild Lohse, Katharina Landfester, Ingo Lieberwirth, Panagiotis L. Kastritis, Anja Harder
bioRxiv
Posted February 16th 2025
Strategies for Mitigating Radiation Damage and Improving Data Completeness in 3D Electron Diffraction of Protein Crystals
Alaa Shaikhqasem, Farzad Hamdi, Lisa Machner, Christoph Parthier, Constanze Breithaupt, Fotis L. Kyrilis, Stephan M. Feller, Panagiotis L. Kastritis, Milton T. Stubbs
bioRxiv
Posted February 6th 2025
Conserved hydrophilic checkpoints tune FocA-mediated formate:H+ symport
Tüting C, Janson K, Kammel M, Ihling C, Lorenz J, Kyrilis FL, Hamdi F, Erdmann C, Sinz A, Sawers RG, Kastritis PL
Nature Communications
Published October 27th 2025
Sense and sensitivity – decoding calcium signalling across cellular, autocrine, paracrine and endocrine pathways in plant resilience
Sarah Lederer, Anja Liese, Justin Lee and Tina Romeis
Current Opinion in Plant Biology, Volume 87
Published October 2025
Transient ligand contacts of the intrinsically disordered N-terminus of neuropeptide Y2 receptor regulate arrestin-3 recruitment
Anette Kaiser, Juan C. Rojas Echeverri, Asat Baischew, Maik Pankonin, Karl D. Leitner, Claudio Iacobucci , Davide Sala, Christian Ihling, Ronny Müller, Rok Ferenc, Annette G. Beck-Sickinger, Peter Schmidt, Jens Meiler, Peter W. Hildebrand & Andrea Sinz
Nature Communications
Published September 19th 2025
Direct evidence of acid-driven protein desolvation
Farzad Hamdi, Ioannis Skalidis, Inken Kaja Schwerin, Jaydeep Belapure, Dmitry A. Semchonok, Fotis L. Kyrilis, Christian Tüting, Johannes Müller, Georg Künze, Panagiotis L. Kastritis
bioRxiv
Posted Spetember 1st 2025
Comprehensive analysis of regulated cell death pathways: intrinsic disorder, protein-protein interactions, and cross-pathway communication
Oleksandr Sorokin, Frank Hause, Alice Wedler, Tala Alakhras, Theresa Bauchspiess, Anne Dietrich, Wiebke F Günther, Coninika Guha, Kingsley B Obika, Joshua Kraft, Ezgi Mehteroglu, Jan Oehlschläger, Erik Siefke, Mark Tawfeik, Toni K Träger, Florian W Otto, Manuel Weber, Felix Wiebe, Andrea Sinz, Vladimir N Uversky
Apoptosis
Published August 19th 2025
Self-supervised learning for generalizable particle picking in cryo-EM micrographs
Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y
Cell Reports Methods
Published July 21st 2025
Evidence of Heteroepitaxy and Solid Solutions in Lattice Matched Ternary Covalent Organic Framework Systems
Winter A, Lange J, Hamdi F, Kastritis PL, Haase F
Journal of the American Chemical Society
Published June 11th 2025
Development and Characterization of a Fluorinated MS-Cleavable Cross-Linker for Structural Proteomics
Oleksandr Sorokin, Frank Hause, Christian H. Ihling, Tomáš Vranka, Václav Matoušek, Andrea Sinz
Journal of the American Society for Mass Spectrometry
Published June 4th 2025
A Polyproline type II Peptidomimetic Disrupts a Grb2 SH3C Domain Protein-protein Interaction Implicated in Breast Cancer
James Luccarelli, Philip C. Simister, Andrew D. Hamilton, Stephan M. Feller, and Sam Thompson
ChemBioChem
Published May 16th 2025