2025

Transient ligand contacts of the intrinsically disordered N-terminus of neuropeptide Y2 receptor regulate arrestin-3 recruitment

Anette Kaiser, Juan C. Rojas Echeverri, Asat Baischew, Maik Pankonin, Karl D. Leitner, Claudio Iacobucci , Davide Sala, Christian Ihling, Ronny Müller, Rok Ferenc, Annette G. Beck-Sickinger, Peter Schmidt, Jens Meiler, Peter W. Hildebrand & Andrea Sinz

Nature Communications

Published September 19th 2025

https://doi.org/10.1038/s41467-025-64051-4

Development and Characterization of a Fluorinated MS-Cleavable Cross-Linker for Structural Proteomics

Oleksandr Sorokin, Frank Hause, Christian H. Ihling, Tomáš Vranka, Václav Matoušek, Andrea Sinz

Journal of the American Society for Mass Spectrometry

Published June 4th 2025

https://doi.org/10.1021/jasms.4c00489

A Polyproline type II Peptidomimetic Disrupts a Grb2 SH3C Domain Protein-protein Interaction Implicated in Breast Cancer

James Luccarelli, Philip C. Simister, Andrew D. Hamilton, Stephan M. Feller, and Sam Thompson

ChemBioChem

Published May 16th 2025

https://doi.org/10.1002/cbic.202500343