Anne Dietrich studied Pharmacy at Martin Luther University Halle-Wittenberg, Germany. During her diploma thesis in Medicinal Chemistry, she focused on the design, synthesis and structural characterization of small-molecule inhibitors targeting parasitic histone deacetylases as potential starting points for the treatment of malaria and schistosomiasis. Her work involved organic synthesis, purification and analytical characterization using High-Performance Liquid Chromatography (HPLC), mass spectrometry (MS) and NMR spectroscopy.
She is currently doing her PhD in the field of protein biochemistry and structural biophysics. She investigates the intrinsically disordered signaling platform Gab1 and its interactions with Src homology 2 (SH2) domain-containing inositol 5-phosphatases (SHIP1 and SHIP2). Her methodological expertise includes recombinant protein expression and purification (FPLC), Nuclear Magnetic Resonance (NMR) spectroscopy, Circular Dichroism (CD), Isothermal Titration Calorimetry (ITC), UV/Vis spectroscopy, and quantitative protein–protein interaction analysis. Her work combines experimental biophysics with computational approaches to characterize structure–function relationships in dynamic protein systems.
Contact
Martin-Luther-Universität Halle-Wittenberg
Charles-Tanford-Proteinzentrum
AG Prof. Dr. Stephan Michael Feller
Kurth-Mothes-Straße 3a
06120 Halle (Saale)
Phone: +49 (0)345 – 5573886
Email: anne.dietrich@pharmazie.uni-halle.de